Reconstitution of Mycobacterium marinum Nonhomologous DNA End Joining Pathway in Leishmania
ABSTRACT In mammalian cells, DNA double-strand breaks (DSBs) are mainly repaired by nonhomologous end joining (NHEJ) pathway. Ku (a heterodimer formed by Ku70 and Ku80 proteins) and DNA ligase IV are the core NHEJ factors. Ku could also be involved in other cellular processes, including telomere len...
| Autores principales: | , , , |
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| Formato: | Artículo |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2022-06-01
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| Colección: | mSphere |
| Materias: | |
| Acceso en línea: | https://journals.asm.org/doi/10.1128/msphere.00156-22 |