Long non-coding RNA GRASLND enhances chondrogenesis via suppression of the interferon type II signaling pathway

Long non-coding RNA GRASLND enhances chondrogenesis via suppression of the interferon type II signaling pathway

The roles of long noncoding RNAs (lncRNAs) in musculoskeletal development, disease, and regeneration remain poorly understood. Here, we identified the novel lncRNA GRASLND (originally named RNF144A-AS1) as a regulator of mesenchymal stem cell (MSC) chondrogenesis. GRASLND, a primate-specific lncRNA,...

Full description

Bibliographic Details
Main Authors: Nguyen PT Huynh, Catherine C Gloss, Jeremiah Lorentz, Ruhang Tang, Jonathan M Brunger, Audrey McAlinden, Bo Zhang, Farshid Guilak
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-03-01
Series:eLife
Subjects:
mesenchymal stem cells
tissue engineering
regenerative medicine
RNF144A-AS1
Online Access:https://elifesciences.org/articles/49558

Internet

https://elifesciences.org/articles/49558

Similar Items