Automated Synthesis of Fluorine-18 Labeled CXCR4 Ligand via the Conjugation with Nicotinic Acid <i>N</i>-Hydroxysuccinimide Ester (6-[<sup>18</sup>F]SFPy)

The C-X-C motif chemokine receptor 4 (CXCR4) is a seven-transmembrane G protein-coupled receptor that is overexpressed in numerous diseases, particularly in various cancers and is a powerful chemokine, attracting cells to the bone marrow niche. Therefore, CXCR4 is an attractive target for imaging an...

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Bibliographic Details
Main Authors: Falguni Basuli, Xiang Zhang, Tim E. Phelps, Elaine M. Jagoda, Peter L. Choyke, Rolf E. Swenson
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/17/3924