Fluconazole alters the polysaccharide capsule of Cryptococcus gattii and leads to distinct behaviors in murine Cryptococcosis.

Cryptococcus gattii is an emergent human pathogen. Fluconazole is commonly used for treatment of cryptococcosis, but the emergence of less susceptible strains to this azole is a global problem and also the data regarding fluconazole-resistant cryptococcosis are scarce. We evaluate the influence of f...

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Main Authors: Julliana Ribeiro Alves Santos, Rodrigo Assunção Holanda, Susana Frases, Mayara Bravim, Glauber de S Araujo, Patrícia Campi Santos, Marliete Carvalho Costa, Maira Juliana Andrade Ribeiro, Gabriella Freitas Ferreira, Ludmila Matos Baltazar, Aline Silva Miranda, Danilo Bretas Oliveira, Carolina Maria Araújo Santos, Alide Caroline Lima Fontes, Ludmila Ferreira Gouveia, Maria Aparecida Resende-Stoianoff, Jonatas Santos Abrahão, Antônio Lúcio Teixeira, Tatiane Alves Paixão, Danielle G Souza, Daniel Assis Santos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4231059?pdf=render