Multi-omics data integration and modeling unravels new mechanisms for pancreatic cancer and improves prognostic prediction

Abstract Pancreatic ductal adenocarcinoma (PDAC), has recently been found to be a heterogeneous disease, although the extension of its diversity remains to be fully understood. Here, we harmonize transcriptomic profiles derived from both PDAC epithelial and microenvironment cells to develop a Master...

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Bibliographic Details
Main Authors: Nicolas A. Fraunhoffer, Analía Meilerman Abuelafia, Martin Bigonnet, Odile Gayet, Julie Roques, Remy Nicolle, Gwen Lomberk, Raul Urrutia, Nelson Dusetti, Juan Iovanna
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-022-00299-z