Liquid application dosing alters the physiology of air-liquid interface (ALI) primary human bronchial epithelial cell/lung fibroblast co-cultures and in vitro testing relevant endpoints

Liquid application dosing alters the physiology of air-liquid interface (ALI) primary human bronchial epithelial cell/lung fibroblast co-cultures and in vitro testing relevant endpoints

Differentiated primary human bronchial epithelial cell (dpHBEC) cultures grown under air-liquid interface (ALI) conditions exhibit key features of the human respiratory tract and are thus critical for respiratory research as well as efficacy and toxicity testing of inhaled substances (e.g., consumer...

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Bibliographic Details
Main Authors: Nicholas M. Mallek, Elizabeth M. Martin, Lisa A. Dailey, Shaun D. McCullough
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Toxicology
Subjects:
inhalation
IVIVE
new approach methodologies (NAMs)
air-liquid interface (ALI)
epithelial
risk assessment
Online Access:https://www.frontiersin.org/articles/10.3389/ftox.2023.1264331/full

Internet

https://www.frontiersin.org/articles/10.3389/ftox.2023.1264331/full

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