Unveiling the Relationship between Structure and Anticancer Properties of Permethylated Anigopreissin A: A Study with Thirteen Analogues

Unveiling the Relationship between Structure and Anticancer Properties of Permethylated Anigopreissin A: A Study with Thirteen Analogues

Permethylated anigopreissin A (PAA), a fully protected form of the natural anigopreissin A, was found in our previous study to be active against several cancer cells, up to IC50 0.24 μM for HepG2 cells. Herein, a total of thirteen PAA analogues with variations in the number, position of substituents...

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Bibliographic Details
Main Authors: Ilaria Caivano, Alessandro Santarsiere, Mario Amati, Paolo Convertini, Maria Funicello, Paolo Lupattelli, Lucia Chiummiento, Anna Santarsiero
Format: Article
Language:English
Published: MDPI AG 2024-08-01
Series:Organics
Subjects:
permethylated anigopreissin A
resveratrol dimer
divergent synthesis
antiproliferative effect
hepatocellular carcinoma cells
Online Access:https://www.mdpi.com/2673-401X/5/3/12

Internet

https://www.mdpi.com/2673-401X/5/3/12

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