Construction and Clinical Translation of Causal Pan-Cancer Gene Score Across Cancer Types

Pan-cancer strategy, an integrative analysis of different cancer types, can be used to explain oncogenesis and identify biomarkers using a larger statistical power and robustness. Fine-mapping defines the casual loci, whereas genome-wide association studies (GWASs) typically identify thousands of ca...

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Bibliographic Details
Main Authors: Shiyue Tao, Xiangyu Ye, Lulu Pan, Minghan Fu, Peng Huang, Zhihang Peng, Sheng Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.784775/full