Altered function of ventral striatum during reward-based decision making in old age

Normal aging is associated with a decline in different cognitive domains and local structural atrophy as well as decreases in dopamine concentration and receptor density. To date, it is largely unknown how these reductions in dopaminergic neurotransmission affect human brain regions responsible for...

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Bibliographic Details
Main Authors: Thomas Mell, Isabell Wartenburger, Alexander Marschner, Arno Villringer, Friedel M Reischies, Hauke R Heekeren
Format: Article
Language:English
Published: Frontiers Media S.A. 2009-10-01
Series:Frontiers in Human Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/neuro.09.034.2009/full