Evaluating stability of attenuated Sabin and two novel type 2 oral poliovirus vaccines in children
Abstract Novel oral poliovirus vaccine type 2 (nOPV2) is being developed to reduce the rare occurrence of disease and outbreaks associated with the genetic instability of the Sabin vaccine strains. Children aged 1 to 5 years were enrolled in two related clinical studies to assess safety, immunogenic...
Main Authors: | , , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-02-01
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Series: | npj Vaccines |
Online Access: | https://doi.org/10.1038/s41541-022-00437-5 |