Wnts in action: from synapse formation to synaptic maintenance

A proper balance between synapse assembly and disassembly are crucial for the formation of functional neuronal circuits and synaptic plasticity in the adult brain. During development, synaptogenesis generates a vast excess of synapses, which are subsequently eliminated. Importantly, aberrant synapti...

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Bibliographic Details
Main Author: Patricia C Salinas
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00162/full