Improvement of protein production in baculovirus expression vector system by removing a total of 10 kb of nonessential fragments from Autographa californica multiple nucleopolyhedrovirus genome

Improvement of protein production in baculovirus expression vector system by removing a total of 10 kb of nonessential fragments from Autographa californica multiple nucleopolyhedrovirus genome

Baculovirus expression vector system (BEVS) is a powerful and versatile platform for recombinant protein production in insect cells. As the most frequently used baculovirus, Autographa californica multiple nucleopolyhedrovirus (AcMNPV) encodes 155 open reading frames (ORFs), including a considerable...

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Bibliographic Details
Main Authors: Xiaoyue Zhang, Aiping He, Yuyu Zong, Houlu Tian, Zhihui Zhang, Kaixia Zhao, Xiaodong Xu, Hongying Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Microbiology
Subjects:
baculovirus expression vector system
Autographa californica multiple nucleopolyhedrovirus
non-essential genes
protein production
gene knockout
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1171500/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2023.1171500/full

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