Effects of Inhibiting Dipeptidyl Peptidase-4 (DPP4) in Cows with Subclinical Ketosis.

The inhibition of dipeptidyl peptidase-4 (DPP4) via specific inhibitors is known to result in improved glucose tolerance and insulin sensitivity and decreased accumulation of hepatic fat in type II diabetic human patients. The metabolic situation of dairy cows can easily be compared to the status of...

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Main Authors: Kirsten Schulz, Jana Frahm, Susanne Kersten, Ulrich Meyer, Jürgen Rehage, Marion Piechotta, Maria Meyerholz, Gerhard Breves, Dania Reiche, Helga Sauerwein, Sven Dänicke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4546328?pdf=render