5-FU-miR-15a Inhibits Activation of Pancreatic Stellate Cells by Reducing YAP1 and BCL-2 Levels In Vitro

5-FU-miR-15a Inhibits Activation of Pancreatic Stellate Cells by Reducing YAP1 and BCL-2 Levels In Vitro

Chronic pancreatitis is characterized by chronic inflammation and fibrosis, processes heightened by activated pancreatic stellate cells (PSCs). Recent publications have demonstrated that miR-15a, which targets <i>YAP1</i> and <i>BCL-2</i>, is significantly downregulated in pa...

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Bibliographic Details
Main Authors: Vanessa M. Diaz Almanzar, Kunal Shah, Joseph F. LaComb, Aisharja Mojumdar, Hetvi R. Patel, Jacky Cheung, Meiyi Tang, Jingfang Ju, Agnieszka B. Bialkowska
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
pancreatic stellate cells
chronic pancreatitis
microRNA
Online Access:https://www.mdpi.com/1422-0067/24/4/3954

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https://www.mdpi.com/1422-0067/24/4/3954

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