Selenite selectively kills lung fibroblasts to treat bleomycin-induced pulmonary fibrosis

Selenite selectively kills lung fibroblasts to treat bleomycin-induced pulmonary fibrosis

Background: Interstitial lung disease (ILD) treatment is a critical unmet need. Selenium is an essential trace element for human life and an antioxidant that activates glutathione, but the gap between its necessity and its toxicity is small and requires special attention. Whether selenium can be use...

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Bibliographic Details
Main Authors: Jiun-Han Lin, Chen-Chi Liu, Chao-Yu Liu, Tien-Wei Hsu, Yi-Chen Yeh, Chorng-Kuang How, Han-Shui Hsu, Shih-Chieh Hung
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Redox Biology
Subjects:
Selenium
Pulmonary fibrosis
Apoptosis
ROS
Glutathione reductase
Thioredoxin reductase
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231724001241

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http://www.sciencedirect.com/science/article/pii/S2213231724001241

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