The role of extracellular vesicles and interleukin-8 in regulating and mediating neutrophil-dependent cancer drug resistance

The role of extracellular vesicles and interleukin-8 in regulating and mediating neutrophil-dependent cancer drug resistance

Tumor drug resistance is a multifactorial and heterogenous condition that poses a serious burden in clinical oncology. Given the increasing incidence of resistant tumors, further understanding of the mechanisms that make tumor cells able to escape anticancer drug effects is pivotal for developing ne...

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Bibliographic Details
Main Authors: Mara Zippoli, Anna Ruocco, Rubina Novelli, Francesca Rocchio, Martina Sara Miscione, Marcello Allegretti, Maria Candida Cesta, Pier Giorgio Amendola
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Oncology
Subjects:
drug resistance
neutrophil
interleukin-8
extracellular vesicles
Tumor-associated neutrophils
NETosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.947183/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.947183/full

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