HIV-1 diversity and pre-treatment drug resistance in the era of integrase inhibitor among newly diagnosed ART-naïve adult patients in Luanda, Angola

HIV-1 diversity and pre-treatment drug resistance in the era of integrase inhibitor among newly diagnosed ART-naïve adult patients in Luanda, Angola

Abstract The surveillance of drug resistance in the HIV-1 naïve population remains critical to optimizing the effectiveness of antiretroviral therapy (ART), mainly in the era of integrase strand transfer inhibitor (INSTI) regimens. Currently, there is no data regarding resistance to INSTI in Angola...

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Bibliographic Details
Main Authors: Cruz S. Sebastião, Ana B. Abecasis, Domingos Jandondo, Joana M. K. Sebastião, João Vigário, Felícia Comandante, Marta Pingarilho, Bárbara Pocongo, Edson Cassinela, Fátima Gonçalves, Perpétua Gomes, Marta Giovanetti, Ngiambudulu M. Francisco, Euclides Sacomboio, Miguel Brito, Jocelyne Neto de Vasconcelos, Joana Morais, Victor Pimentel
Format: Article
Language:English
Published: Nature Portfolio 2024-07-01
Series:Scientific Reports
Subjects:
HIV-1
Genetic diversity
Drug resistance mutations
INSTI
NGS
Angola
Online Access:https://doi.org/10.1038/s41598-024-66905-1

Internet

https://doi.org/10.1038/s41598-024-66905-1

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