The Development of FAK Inhibitors: A Five-Year Update

The Development of FAK Inhibitors: A Five-Year Update

Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase over-expressed in different solid cancers. In recent years, FAK has been recognized as a new target for the development of antitumor agents, useful to contrast tumor development and metastasis formation. To date, studies on the role of FA...

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Bibliographic Details
Main Authors: Andrea Spallarossa, Bruno Tasso, Eleonora Russo, Carla Villa, Chiara Brullo
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
focal adhesion kinase
FAK inhibitors
anticancer compounds
medicinal chemistry
PROTAC
pyrimidines
Online Access:https://www.mdpi.com/1422-0067/23/12/6381

Internet

https://www.mdpi.com/1422-0067/23/12/6381

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