GDF15 propeptide promotes bone metastasis of castration-resistant prostate cancer by augmenting the bone microenvironment

GDF15 propeptide promotes bone metastasis of castration-resistant prostate cancer by augmenting the bone microenvironment

Abstract Background Bone metastasis (BM) is a common and fatal condition in patients with castration-resistant prostate cancer (CRPC). However, there are no useful blood biomarkers for CRPC with BM, and the mechanism underlying BM is unclear. In this study, we investigated precise blood biomarkers f...

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Bibliographic Details
Main Authors: Gaku Yamamichi, Taigo Kato, Noriaki Arakawa, Yoko Ino, Takeshi Ujike, Kosuke Nakano, Yoko Koh, Yuichi Motoyama, Hidetatsu Outani, Shohei Myoba, Yu Ishizuya, Yoshiyuki Yamamoto, Koji Hatano, Atsunari Kawashima, Shinichiro Fukuhara, Hiroji Uemura, Seiji Okada, Eiichi Morii, Norio Nonomura, Motohide Uemura
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Biomarker Research
Subjects:
Castration-resistant prostate cancer
Bone metastasis
GDF15
Biomarker
Online Access:https://doi.org/10.1186/s40364-024-00695-6

Internet

https://doi.org/10.1186/s40364-024-00695-6

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