DNA Methylation Epigenetically Regulates Gene Expression in Burkholderia cenocepacia and Controls Biofilm Formation, Cell Aggregation, and Motility

ABSTRACT Respiratory tract infections by the opportunistic pathogen Burkholderia cenocepacia often lead to severe lung damage in cystic fibrosis (CF) patients. New insights in how to tackle these infections might emerge from the field of epigenetics, as DNA methylation is an important regulator of g...

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Bibliographic Details
Main Authors: Ian Vandenbussche, Andrea Sass, Marta Pinto-Carbó, Olga Mannweiler, Leo Eberl, Tom Coenye
Format: Article
Language:English
Published: American Society for Microbiology 2020-08-01
Series:mSphere
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/msphere.00455-20