A monoamine oxidase B inhibitor ethyl ferulate suppresses microglia-mediated neuroinflammation and alleviates ischemic brain injury

A monoamine oxidase B inhibitor ethyl ferulate suppresses microglia-mediated neuroinflammation and alleviates ischemic brain injury

Microglia are the resident macrophages in the brain, which play a critical role in post-stroke neuroinflammation. Accordingly, targeting neuroinflammation could be a promising strategy to improve ischemic stroke outcomes. Ethyl ferulate (EF) has been confirmed to possess anti-inflammatory properties...

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Bibliographic Details
Main Authors: Xinxin Zou, Shenghan Gao, Jiangnan Li, Chenggang Li, Chuyu Wu, Xiang Cao, Shengnan Xia, Pengfei Shao, Xinyu Bao, Haiyan Yang, Pinyi Liu, Yun Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
Subjects:
ethyl ferulate
ischemic stroke
microglia
neuroinflammation
monoamine oxidase B
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1004215/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.1004215/full

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