Microisolation of Spatially Characterized Single Populations of Neurons for RNA Sequencing from Mouse and Postmortem Human Brain Tissues

Microisolation of Spatially Characterized Single Populations of Neurons for RNA Sequencing from Mouse and Postmortem Human Brain Tissues

Single-cell and single-population RNA sequencing (RNA-seq) is a rapidly evolving new field of intense investigation. Recent studies indicate unique transcriptomic profiles are derived based on the spatial localization of neurons within circuits and regions. Individual neuronal subtypes can have vast...

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Bibliographic Details
Main Authors: Melissa J. Alldred, Stephen D. Ginsberg
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Journal of Clinical Medicine
Subjects:
RNA-seq
laser capture microdissection
selective vulnerability
bioinformatics
single population
spatial profiling
Online Access:https://www.mdpi.com/2077-0383/12/9/3304

Internet

https://www.mdpi.com/2077-0383/12/9/3304

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