Down-regulation of claudin-18 is associated with the proliferative and invasive potential of gastric cancer at the invasive front.

BACKGROUND: Claudins are known as tight junction proteins, and their expression pattern in gastric cancer is still controversial. The relationship between the expression patterns of tight junction proteins and tumor proliferation in early gastric cancer is still far from clear. AIMS: To investigate...

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Bibliographic Details
Main Authors: Tadayuki Oshima, Jing Shan, Takuya Okugawa, Xin Chen, Kazutoshi Hori, Toshihiko Tomita, Hirokazu Fukui, Jiro Watari, Hiroto Miwa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3779237?pdf=render