CDC42-mediated Wnt signaling facilitates odontogenic differentiation of DPCs during tooth root elongation

CDC42-mediated Wnt signaling facilitates odontogenic differentiation of DPCs during tooth root elongation

Abstract Background CDC42 is a member of Rho GTPase family, acting as a molecular switch to regulate cytoskeleton organization and junction maturation of epithelium in organ development. Tooth root pattern is a highly complicated and dynamic process that dependens on interaction of epithelium and me...

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Bibliographic Details
Main Authors: Tao Zhou, Guoqing Chen, Yuchan Xu, Shuning Zhang, Huilin Tang, Tao Qiu, Weihua Guo
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Stem Cell Research & Therapy
Subjects:
Odontogenesis
Tooth root
CDC42 GTP binding protein
Mesenchymal stem cells
Wnt signaling pathway
Online Access:https://doi.org/10.1186/s13287-023-03486-2

Internet

https://doi.org/10.1186/s13287-023-03486-2

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