Substitution of D-Arginine at Position 11 of α-RgIA Potently Inhibits α7 Nicotinic Acetylcholine Receptor

Conotoxins are a class of disulfide-rich peptides found in the venom of cone snails, which have attracted considerable attention in recent years due to their potent activity on ion channels and potential for therapeutics. Among them, α-conotoxin RgIA, a 13-residue peptide, has shown great promise as...

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Bibliographic Details
Main Authors: Yong Wu, Junjie Zhang, Jie Ren, Xiaopeng Zhu, Rui Li, Dongting Zhangsun, Sulan Luo
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Marine Drugs
Subjects:
Online Access:https://www.mdpi.com/1660-3397/21/6/326