Cell Confluence Modulates TRPV4 Channel Activity in Response to Hypoxia

Cell Confluence Modulates TRPV4 Channel Activity in Response to Hypoxia

Transient receptor potential vanilloid 4 (TRPV4) is a polymodal Ca<sup>2+</sup>-permeable channel involved in various hypoxia-sensitive pathophysiological phenomena. Different tools are available to study channel activity, requiring cells to be cultured at specific optimal densities. In...

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Bibliographic Details
Main Authors: Solène Barbeau, Alexandre Joushomme, Yann Chappe, Guillaume Cardouat, Isabelle Baudrimont, Véronique Freund-Michel, Christelle Guibert, Roger Marthan, Patrick Berger, Pierre Vacher, Yann Percherancier, Jean-François Quignard, Thomas Ducret
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Biomolecules
Subjects:
BRET
calcium
cell culture conditions
cell density
patch-clamp
stretch-activated channel
Online Access:https://www.mdpi.com/2218-273X/12/7/954

Internet

https://www.mdpi.com/2218-273X/12/7/954

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