Investigation of biopharmaceutical and physicochemical drug properties suitable for orally disintegrating tablets

The purpose of this study was to evaluate the biopharmaceutical drug properties suitable for orally disintegrating tablets (ODTs). The net charge at pH 7.4, log D6.5, the highest dose strength, solubility in water, dose number, and elimination t1/2 of 57 ODT drugs and 113 drugs of immediate-release...

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Bibliographic Details
Main Authors: Asami Ono, Takumi Tomono, Takuo Ogihara, Katsuhide Terada, Kiyohiko Sugano
Format: Article
Language:English
Published: International Association of Physical Chemists (IAPC) 2016-12-01
Series:ADMET and DMPK
Subjects:
Online Access:http://pub.iapchem.org/ojs/index.php/admet/article/view/338