Kras promotes myeloid differentiation through Wnt/β‐catenin signaling

Abstract Wild‐type Kras, a small GTPase, inactivates Ras growth‐promoting signaling. However, the role of Kras in differentiation of myeloid cells remains unclear. This study showed the involvement of Kras in a novel regulatory mechanism underlying the dimethyl sulfoxide (DMSO)‐induced differentiati...

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Bibliographic Details
Main Authors: Noriko Yokoyama, Yeon‐Jeong Kim, Yoshio Hirabayashi, Yoko Tabe, Kenji Takamori, Hideoki Ogawa, Kazuhisa Iwabuchi
Format: Article
Language:English
Published: Wiley 2019-07-01
Series:FASEB BioAdvances
Subjects:
Online Access:https://doi.org/10.1096/fba.2019-00004