Dimerization of hepatitis E virus capsid protein E2s domain is essential for virus-host interaction.

Hepatitis E virus (HEV), a non-enveloped, positive-stranded RNA virus, is transmitted in a faecal-oral manner, and causes acute liver diseases in humans. The HEV capsid is made up of capsomeres consisting of homodimers of a single structural capsid protein forming the virus shell. These dimers are b...

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Bibliographic Details
Main Authors: Shaowei Li, Xuhua Tang, J Seetharaman, Chunyan Yang, Ying Gu, Jun Zhang, Hailian Du, J Wai Kuo Shih, Choy-Leong Hew, J Sivaraman, Ningshao Xia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2714988?pdf=render