Characterization and Vector Competence Studies of Chikungunya Virus Lacking Repetitive Motifs in the 3′ Untranslated Region of the Genome

Characterization and Vector Competence Studies of Chikungunya Virus Lacking Repetitive Motifs in the 3′ Untranslated Region of the Genome

Using reverse genetics, we analyzed a chikungunya virus (CHIKV) isolate of the Indian Ocean lineage lacking direct repeat (DR) elements in the 3′ untranslated region, namely DR1a and DR2a. While this deletion mutant CHIKV-∆DR exhibited growth characteristics comparable to the wild-type virus in Baby...

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Bibliographic Details
Main Authors: Yauhen Karliuk, Anja vom Hemdt, Janett Wieseler, Martin Pfeffer, Beate M. Kümmerer
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Viruses
Subjects:
chikungunya virus
vector competence
3′ untranslated region
direct repeats
<i>Aedes vexans</i>
<i>Culex pipiens</i>
Online Access:https://www.mdpi.com/1999-4915/13/3/403

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https://www.mdpi.com/1999-4915/13/3/403

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