Ascaris lumbricoides coinfection reduces tissue damage by decreasing IL-6 levels without altering clinical evolution of pulmonary tuberculosis or Th1/Th2/Th17 cytokine profile

Ascaris lumbricoides coinfection reduces tissue damage by decreasing IL-6 levels without altering clinical evolution of pulmonary tuberculosis or Th1/Th2/Th17 cytokine profile

Abstract INTRODUCTION: Immunological control of Mycobacterium tuberculosis infection is dependent on the cellular immune response, mediated predominantly by Th1 type CD4+ T cells. Polarization of the immune response to Th2 can inhibit the host immune protection against pathogens. Patients with tub...

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Bibliographic Details
Main Authors: João Hugo Abdalla Santos, Samira Bührer-Sékula, Gisely Cardoso Melo, Marcelo Cordeiro-Santos, João Paulo Diniz Pimentel, Adriano Gomes-Silva, Allyson Guimarães Costa, Valeria Saraceni, Alda Maria Da-Cruz, Marcus Vinícius Guimarães Lacerda
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2019-12-01
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Mycobacterium tuberculosis
Helminths
Coinfection
Cellular immunity
Cytokines
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100347&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100347&tlng=en

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