Aryl Hydrocarbon Receptor (AhR)-Mediated Signaling in iPSC-Derived Human Motor Neurons

Aryl Hydrocarbon Receptor (AhR)-Mediated Signaling in iPSC-Derived Human Motor Neurons

Exposure to environmental pollutants and endogenous metabolites that induce aryl hydrocarbon receptor (AhR) expression has been suggested to affect cognitive development and, particularly in boys, also motor function. As current knowledge is based on epidemiological and animal studies, in vitro mode...

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Bibliographic Details
Main Authors:	Saima Jalil Imran, Barbora Vagaska, Jan Kriska, Miroslava Anderova, Mario Bortolozzi, Gino Gerosa, Patrizia Ferretti, Radim Vrzal
Format:	Article
Language:	English
Published:	MDPI AG 2022-07-01
Series:	Pharmaceuticals
Subjects:	hiPSCs AhR motor neurons CYP1A1 CYP1B1 L-Kyn
Online Access:	https://www.mdpi.com/1424-8247/15/7/828

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