Genome-wide association study for grain zinc concentration in bread wheat (Triticum aestivum L.)
IntroductionZinc (Zn) deficiency causes serious diseases in people who rely on cereals as their main food source. However, the grain zinc concentration (GZnC) in wheat is low. Biofortification is a sustainable strategy for reducing human Zn deficiency.MethodsIn this study, we constructed a populatio...
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Frontiers Media S.A.
2023-04-01
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| Series: | Frontiers in Plant Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpls.2023.1169858/full |
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| author | Jianhui Ma Miaomiao Ye Qianqian Liu Meng Yuan Meng Yuan Daijing Zhang Chunxi Li Qingdong Zeng Jianhui Wu Dejun Han Lina Jiang |
| author_facet | Jianhui Ma Miaomiao Ye Qianqian Liu Meng Yuan Meng Yuan Daijing Zhang Chunxi Li Qingdong Zeng Jianhui Wu Dejun Han Lina Jiang |
| author_sort | Jianhui Ma |
| collection | DOAJ |
| description | IntroductionZinc (Zn) deficiency causes serious diseases in people who rely on cereals as their main food source. However, the grain zinc concentration (GZnC) in wheat is low. Biofortification is a sustainable strategy for reducing human Zn deficiency.MethodsIn this study, we constructed a population of 382 wheat accessions and determined their GZnC in three field environments. Phenotype data was used for a genome-wide association study (GWAS) using a 660K single nucleotide polymorphism (SNP) array, and haplotype analysis identified an important candidate gene for GZnC.ResultsWe found that GZnC of the wheat accessions showed an increasing trend with their released years, indicating that the dominant allele of GZnC was not lost during the breeding process. Nine stable quantitative trait loci (QTLs) for GZnC were identified on chromosomes 3A, 4A, 5B, 6D, and 7A. And an important candidate gene for GZnC, namely, TraesCS6D01G234600, and GZnC between the haplotypes of this gene showed, significant difference (P ≤ 0.05) in three environments.DiscussionA novel QTL was first identified on chromosome 6D, this finding enriches our understanding of the genetic basis of GZnC in wheat. This study provides new insights into valuable markers and candidate genes for wheat biofortification to improve GZnC. |
| first_indexed | 2024-04-09T20:01:08Z |
| format | Article |
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| institution | Directory Open Access Journal |
| issn | 1664-462X |
| language | English |
| last_indexed | 2024-04-09T20:01:08Z |
| publishDate | 2023-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Plant Science |
| spelling | doaj.art-a5e887e86dbd46d285e36dd6941fd4052023-04-03T05:15:25ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2023-04-011410.3389/fpls.2023.11698581169858Genome-wide association study for grain zinc concentration in bread wheat (Triticum aestivum L.)Jianhui Ma0Miaomiao Ye1Qianqian Liu2Meng Yuan3Meng Yuan4Daijing Zhang5Chunxi Li6Qingdong Zeng7Jianhui Wu8Dejun Han9Lina Jiang10College of Life Science, Henan Normal University, Xinxiang, ChinaCollege of Life Science, Henan Normal University, Xinxiang, ChinaCollege of Life Science, Henan Normal University, Xinxiang, ChinaCollege of Life Science, Henan Normal University, Xinxiang, ChinaState Key Laboratory of Crop Stress Biology in Arid Areas, Northwest A&F University, Yangling, Shanxi, ChinaCollege of Life Science, Henan Normal University, Xinxiang, ChinaCollege of Life Science, Henan Normal University, Xinxiang, ChinaState Key Laboratory of Crop Stress Biology in Arid Areas, Northwest A&F University, Yangling, Shanxi, ChinaState Key Laboratory of Crop Stress Biology in Arid Areas, Northwest A&F University, Yangling, Shanxi, ChinaState Key Laboratory of Crop Stress Biology in Arid Areas, Northwest A&F University, Yangling, Shanxi, ChinaCollege of Life Science, Henan Normal University, Xinxiang, ChinaIntroductionZinc (Zn) deficiency causes serious diseases in people who rely on cereals as their main food source. However, the grain zinc concentration (GZnC) in wheat is low. Biofortification is a sustainable strategy for reducing human Zn deficiency.MethodsIn this study, we constructed a population of 382 wheat accessions and determined their GZnC in three field environments. Phenotype data was used for a genome-wide association study (GWAS) using a 660K single nucleotide polymorphism (SNP) array, and haplotype analysis identified an important candidate gene for GZnC.ResultsWe found that GZnC of the wheat accessions showed an increasing trend with their released years, indicating that the dominant allele of GZnC was not lost during the breeding process. Nine stable quantitative trait loci (QTLs) for GZnC were identified on chromosomes 3A, 4A, 5B, 6D, and 7A. And an important candidate gene for GZnC, namely, TraesCS6D01G234600, and GZnC between the haplotypes of this gene showed, significant difference (P ≤ 0.05) in three environments.DiscussionA novel QTL was first identified on chromosome 6D, this finding enriches our understanding of the genetic basis of GZnC in wheat. This study provides new insights into valuable markers and candidate genes for wheat biofortification to improve GZnC.https://www.frontiersin.org/articles/10.3389/fpls.2023.1169858/fullTriticum aestivum L.grain Zn concentrationgenome-wide association studyquantitative trait locicandidate gene |
| spellingShingle | Jianhui Ma Miaomiao Ye Qianqian Liu Meng Yuan Meng Yuan Daijing Zhang Chunxi Li Qingdong Zeng Jianhui Wu Dejun Han Lina Jiang Genome-wide association study for grain zinc concentration in bread wheat (Triticum aestivum L.) Frontiers in Plant Science Triticum aestivum L. grain Zn concentration genome-wide association study quantitative trait loci candidate gene |
| title | Genome-wide association study for grain zinc concentration in bread wheat (Triticum aestivum L.) |
| title_full | Genome-wide association study for grain zinc concentration in bread wheat (Triticum aestivum L.) |
| title_fullStr | Genome-wide association study for grain zinc concentration in bread wheat (Triticum aestivum L.) |
| title_full_unstemmed | Genome-wide association study for grain zinc concentration in bread wheat (Triticum aestivum L.) |
| title_short | Genome-wide association study for grain zinc concentration in bread wheat (Triticum aestivum L.) |
| title_sort | genome wide association study for grain zinc concentration in bread wheat triticum aestivum l |
| topic | Triticum aestivum L. grain Zn concentration genome-wide association study quantitative trait loci candidate gene |
| url | https://www.frontiersin.org/articles/10.3389/fpls.2023.1169858/full |
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