CCP5 and CCP6 retain CP110 and negatively regulate ciliogenesis

CCP5 and CCP6 retain CP110 and negatively regulate ciliogenesis

Abstract Background The axonemal microtubules of primary cilium undergo a conserved protein posttranslational modification (PTM) — polyglutamylation. This reversible procedure is processed by tubulin tyrosine ligase-like polyglutamylases to form secondary polyglutamate side chains, which are metabol...

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Bibliografski detalji
Glavni autori: Yujuan Wang, Yuan Zhang, Xinyu Guo, Yiqiang Zheng, Xinjie Zhang, Shanshan Feng, Hui-Yuan Wu
Format: Članak
Jezik:English
Izdano: BMC 2023-05-01
Serija:BMC Biology
Teme:
CCP5
CCP6
Polyglutamylation
Ciliogenesis
CP110
Online pristup:https://doi.org/10.1186/s12915-023-01622-1

Internet

https://doi.org/10.1186/s12915-023-01622-1

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