mPR-Specific Actions Influence Maintenance of the Blood–Brain Barrier (BBB)

Cerebral cavernous malformations (CCMs) are characterized by abnormally dilated intracranial microvascular sinusoids that result in increased susceptibility to hemorrhagic stroke. It has been demonstrated that three CCM proteins (CCM1, CCM2, and CCM3) form the CCM signaling complex (CSC) to mediate...

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Bibliographic Details
Main Authors: Johnathan Abou-Fadel, Xiaoting Jiang, Akhil Padarti, Dinesh G. Goswami, Mark Smith, Brian Grajeda, Muaz Bhalli, Alexander Le, Wendy E. Walker, Jun Zhang
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/17/9684