Two distinct degenerative types of nigrostriatal dopaminergic neuron in the early stage of parkinsonian disorders

Two distinct degenerative types of nigrostriatal dopaminergic neuron in the early stage of parkinsonian disorders

Introduction: The present study characterized the degeneration of nigrostriatal dopaminergic neurons in the early stages of parkinsonian disorders using integrative neuroimaging analysis with neuromelanin-sensitive MRI and 123I-FP-CIT dopamine transporter (DAT) SPECT. Methods: Thirty-one, 30, and 29...

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Bibliographic Details
Main Authors: Tomoya Kawazoe, Keizo Sugaya, Yasuhiro Nakata, Masato Okitsu, Kazushi Takahashi
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Clinical Parkinsonism & Related Disorders
Subjects:
Nigrostriatal dopaminergic degeneration
Neuromelanin-sensitive MRI
Dopamine transporter SPECT
Corticobasal degeneration
Progressive supranuclear palsy
Multiple system atrophy
Online Access:http://www.sciencedirect.com/science/article/pii/S2590112524000112

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http://www.sciencedirect.com/science/article/pii/S2590112524000112

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