Leocarpinolide B Attenuates Collagen Type II-Induced Arthritis by Inhibiting DNA Binding Activity of NF-κB

Leocarpinolide B Attenuates Collagen Type II-Induced Arthritis by Inhibiting DNA Binding Activity of NF-κB

Rheumatoid arthritis (RA) is a chronic autoimmune disease triggered by a cascading inflammatory response. Sigesbeckia Herba (SH) has long been utilized as a traditional remedy to alleviate symptoms associated with rheumatism. Our previous study found that leocarpinolide B (LB), a sesquiterpene lacto...

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Bibliographic Details
Main Authors: Ke-Gang Linghu, Guan-Ding Zhao, Dai-Yan Zhang, Shi-Hang Xiong, Guo-Ping Wu, Li-Yu Shen, Wen-Qing Cui, Tian Zhang, Yuan-Jia Hu, Bing Guo, Xiang-Chun Shen, Hua Yu
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Molecules
Subjects:
leocarpinolide B
sesquiterpene lactone
rheumatoid arthritis
NF-κB p65
synovitis
Online Access:https://www.mdpi.com/1420-3049/28/10/4241

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https://www.mdpi.com/1420-3049/28/10/4241

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