Identification of Compounds With Antiviral Activity Against SARS-CoV-2 in the MMV Pathogen Box Using a Phenotypic High-Throughput Screening Assay

Identification of Compounds With Antiviral Activity Against SARS-CoV-2 in the MMV Pathogen Box Using a Phenotypic High-Throughput Screening Assay

Until December 2021, the COVID-19 pandemic has caused more than 5.5 million deaths. Vaccines are being deployed worldwide to mitigate severe disease and death, but continued transmission and the emergence of SARS-CoV-2 variants indicate that specific treatments against COVID-19 are still necessary....

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Bibliographic Details
Main Authors: Laís D. Coimbra, Alexandre Borin, Marina Fontoura, Humberto D. Gravina, Alice Nagai, Jacqueline Farinha Shimizu, Karina Bispo-dos-Santos, Fabiana Granja, Paulo S. L. Oliveira, Kleber G. Franchini, Kirandeep Samby, Marjorie Bruder, José Luiz Proença-Módena, Daniela B. B. Trivella, Juliana H. C. Smetana, Artur T. Cordeiro, Rafael Elias Marques
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Virology
Subjects:
SARS-CoV-2
biosafety level 3
MMV pathogen box
antivirals
drug repositioning
high-throughput screening
Online Access:https://www.frontiersin.org/articles/10.3389/fviro.2022.854363/full

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https://www.frontiersin.org/articles/10.3389/fviro.2022.854363/full

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