Dual Network Hydrogels Incorporated with Bone Morphogenic Protein-7-Loaded Hyaluronic Acid Complex Nanoparticles for Inducing Chondrogenic Differentiation of Synovium-Derived Mesenchymal Stem Cells

Dual Network Hydrogels Incorporated with Bone Morphogenic Protein-7-Loaded Hyaluronic Acid Complex Nanoparticles for Inducing Chondrogenic Differentiation of Synovium-Derived Mesenchymal Stem Cells

Alginate-poloxamer (ALG-POL) copolymer with optimal POL content was synthesized, and it was combined with silk fibroin (SF) for building ALG-POL/SF dual network hydrogels. Hyaluronic acid(HA)/chitosan-poly(dioxanone)(CH-PDO) complex nanoparticles (NPs) with optimized composition and high encapsulati...

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Bibliographic Details
Main Authors: Qing Min, Jiaoyan Liu, Yuchen Zhang, Bin Yang, Ying Wan, Jiliang Wu
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Pharmaceutics
Subjects:
dual network hydrogel
complex nanoparticles
bone morphogenic protein-7
chondrogenic differentiation
synovium-derived mesenchymal stem cells
Online Access:https://www.mdpi.com/1999-4923/12/7/613

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https://www.mdpi.com/1999-4923/12/7/613

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