Longitudinal diffusion and volumetric kinetics of head and neck cancer magnetic resonance on a 1.5 T MR-linear accelerator hybrid system: A prospective R-IDEAL stage 2a imaging biomarker characterization/pre-qualification study

Longitudinal diffusion and volumetric kinetics of head and neck cancer magnetic resonance on a 1.5 T MR-linear accelerator hybrid system: A prospective R-IDEAL stage 2a imaging biomarker characterization/pre-qualification study

Objectives: We aim to characterize the serial quantitative apparent diffusion coefficient (ADC) changes of the target disease volume using diffusion-weighted imaging (DWI) acquired weekly during radiation therapy (RT) on a 1.5 T MR-Linac and correlate these changes with tumor response and oncologic...

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Main Authors: Dina M. El-Habashy, Kareem A. Wahid, Renjie He, Brigid McDonald, Jillian Rigert, Samuel J. Mulder, Tze Yee Lim, Xin Wang, Jinzhong Yang, Yao Ding, Mohamed A. Naser, Sweet Ping Ng, Houda Bahig, Travis C. Salzillo, Kathryn E. Preston, Moamen Abobakr, Mohamed A. Shehata, Enas A. Elkhouly, Hagar A. Alagizy, Amira H. Hegazy, Mustefa Mohammadseid, Chris Terhaard, Marielle Philippens, David I. Rosenthal, Jihong Wang, Stephen Y. Lai, Alex Dresner, John C. Christodouleas, Abdallah Sherif Radwan Mohamed, Clifton D. Fuller
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Clinical and Translational Radiation Oncology
Subjects:
DWI
ADC
MR-Linac
Head and neck cancer
Oncologic outcomes
Diffusion
Online Access:http://www.sciencedirect.com/science/article/pii/S2405630823000915

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http://www.sciencedirect.com/science/article/pii/S2405630823000915

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