A functional analysis of the spacer of V(D)J recombination signal sequences.
During lymphocyte development, V(D)J recombination assembles antigen receptor genes from component V, D, and J gene segments. These gene segments are flanked by a recombination signal sequence (RSS), which serves as the binding site for the recombination machinery. The murine Jbeta2.6 gene segment i...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2003-10-01
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Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC212687?pdf=render |