In vivo effects of histone H3 depletion on nucleosome occupancy and position in Saccharomyces cerevisiae.

Previous studies in Saccharomyces cerevisiae established that depletion of histone H4 results in the genome-wide transcriptional de-repression of hundreds of genes. To probe the mechanism of this transcriptional de-repression, we depleted nucleosomes in vivo by conditional repression of histone H3 t...

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Bibliographic Details
Main Authors: Andrea J Gossett, Jason D Lieb
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3380831?pdf=render