Targeted in vivo epigenome editing of H3K27me3

Targeted in vivo epigenome editing of H3K27me3

Abstract Background Epigenetic modifications have a central role in transcriptional regulation. While several studies using next-generation sequencing have revealed genome-wide associations between epigenetic modifications and transcriptional states, a direct causal relationship at specific genomic...

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Bibliographic Details
Main Authors: Hiroto S. Fukushima, Hiroyuki Takeda, Ryohei Nakamura
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Epigenetics & Chromatin
Subjects:
Epigenome editing
H3K27me3
dCas9
Medaka
Transcriptional regulation
Histone modification
Online Access:http://link.springer.com/article/10.1186/s13072-019-0263-z

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http://link.springer.com/article/10.1186/s13072-019-0263-z

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