Liver X Receptor Activation Attenuates Oxysterol-Induced Inflammatory Responses in Fetoplacental Endothelial Cells

Liver X Receptor Activation Attenuates Oxysterol-Induced Inflammatory Responses in Fetoplacental Endothelial Cells

Oxysterols are oxidized cholesterol derivatives whose systemic levels are found elevated in pregnancy disorders such as gestational diabetes mellitus (GDM). Oxysterols act through various cellular receptors and serve as a key metabolic signal, coordinating inflammation. GDM is a condition of low-gra...

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Bibliographic Details
Main Authors: Meekha George, Magdalena Lang, Chaitanya Chakravarthi Gali, Joshua Adekunle Babalola, Carmen Tam-Amersdorfer, Anika Stracke, Herbert Strobl, Robert Zimmermann, Ute Panzenboeck, Christian Wadsack
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cells
Subjects:
oxysterols
liver X receptors
ATP-binding cassette transporter 1
toll-like receptor 4
placenta
endothelial cells
Online Access:https://www.mdpi.com/2073-4409/12/8/1186

Internet

https://www.mdpi.com/2073-4409/12/8/1186

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