β-Hydroxybutyrate alleviates cartilage senescence through hnRNP A1-mediated up-regulation of PTEN

β-Hydroxybutyrate alleviates cartilage senescence through hnRNP A1-mediated up-regulation of PTEN

Senescence chondrocytes play an important role in Osteoarthritis (OA) progression. However, alleviating OA progression through senescent chondrocyte intervention still faces great challenges. β-Hydroxybutyrate (BHB) exhibits anti-senescence effects in a variety of age-related dis-eases, but its role...

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Bibliographic Details
Main Authors: Guang Xia, Zi Wen, Lina Zhang, Junjie Huang, Xinxing Wang, Chi Liang, Xiaoyu Cui, Xu Cao, Song Wu
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Experimental Gerontology
Subjects:
β-Hydroxybutyrate
Senescent
Osteoarthritis
Phosphatase and tensin homolog
Online Access:http://www.sciencedirect.com/science/article/pii/S053155652300061X

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http://www.sciencedirect.com/science/article/pii/S053155652300061X

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