β-Hydroxybutyrate alleviates cartilage senescence through hnRNP A1-mediated up-regulation of PTEN

β-Hydroxybutyrate alleviates cartilage senescence through hnRNP A1-mediated up-regulation of PTEN

Senescence chondrocytes play an important role in Osteoarthritis (OA) progression. However, alleviating OA progression through senescent chondrocyte intervention still faces great challenges. β-Hydroxybutyrate (BHB) exhibits anti-senescence effects in a variety of age-related dis-eases, but its role...

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Detalles Bibliográficos
Autores principales: Guang Xia, Zi Wen, Lina Zhang, Junjie Huang, Xinxing Wang, Chi Liang, Xiaoyu Cui, Xu Cao, Song Wu
Formato: Artículo
Lenguaje:English
Publicado: Elsevier 2023-05-01
Colección:Experimental Gerontology
Materias:
β-Hydroxybutyrate
Senescent
Osteoarthritis
Phosphatase and tensin homolog
Acceso en línea:http://www.sciencedirect.com/science/article/pii/S053155652300061X

Internet

http://www.sciencedirect.com/science/article/pii/S053155652300061X

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