Exploring the utility and acceptability of Faecal immunochemical testing (FIT) as a novel intervention for the improvement of colorectal Cancer (CRC) surveillance in individuals with lynch syndrome (FIT for lynch study): a single-arm, prospective, multi-centre, non-randomised study

Exploring the utility and acceptability of Faecal immunochemical testing (FIT) as a novel intervention for the improvement of colorectal Cancer (CRC) surveillance in individuals with lynch syndrome (FIT for lynch study): a single-arm, prospective, multi-centre, non-randomised study

Abstract Background Lynch Syndrome (LS) is an inherited cancer predisposition syndrome defined by pathogenic variants in the mismatch repair (MMR) or EPCAM genes. In the United Kingdom, people with LS are advised to undergo biennial colonoscopy from as early as 25 until 75 years of age to mitigate a...

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Bibliographic Details
Main Authors: Anne Lincoln, Sally Benton, Carolyn Piggott, Bernard V. North, Jane Rigney, Caroline Young, Philip Quirke, Peter Sasieni, Kevin J. Monahan
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Cancer
Subjects:
Lynch syndrome
Colorectal Cancer surveillance
Bowel Cancer surveillance
Mismatch repair deficiency
Faecal immunochemical testing (FIT)
Microbiome
Online Access:https://doi.org/10.1186/s12885-022-10217-y

Internet

https://doi.org/10.1186/s12885-022-10217-y

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