Identification of a Novel Serological Marker in Seronegative Rheumatoid Arthritis Using the Peptide Library Approach

Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation mainly affecting the joints leading to cartilage and bone destruction. The definition of seropositive or seronegative RA is based on the presence or absence of rheumatoid factor (RF) and anti-citrullinat...

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Main Authors: Caterina Bason, Alessandro Barbieri, Nicola Martinelli, Bianca Olivieri, Giuseppe Argentino, Elena Bartoloni, Ruggero Beri, Gnaneshwer Jadav, Antonio Puccetti, Elisa Tinazzi, Claudio Lunardi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.753400/full