Adhesion of Crithidia fasciculata promotes a rapid change in developmental fate driven by cAMP signaling

Adhesion of Crithidia fasciculata promotes a rapid change in developmental fate driven by cAMP signaling

ABSTRACT Trypanosomatids are single-celled parasites responsible for human and animal disease. Typically, colonization of an insect host is required for transmission. Stable attachment of parasites to insect tissues via their single flagellum coincides with differentiation and morphological changes....

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Main Authors: Shane Denecke, Madeline F. Malfara, Kelly R. Hodges, Nikki A. Holmes, Andre R. Williams, Julia H. Gallagher-Teske, Julia M. Pascarella, Abigail M. Daniels, Geert Jan Sterk, Rob Leurs, Gordon Ruthel, Rachel Hoang, Megan L. Povelones, Michael Povelones
Format: Article
Language:English
Published: American Society for Microbiology 2024-10-01
Series:mSphere
Subjects:
Crithidia fasciculata
adhesion
attachment
cyclic AMP
signaling
differentiation
Online Access:https://journals.asm.org/doi/10.1128/msphere.00617-24

Internet

https://journals.asm.org/doi/10.1128/msphere.00617-24

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