Polyacetylene Isomers Isolated from <i>Bidens pilosa</i> L. Suppress the Metastasis of Gastric Cancer Cells by Inhibiting Wnt/<i>β</i>-Catenin and Hippo/YAP Signaling Pathways

Polyacetylene Isomers Isolated from <i>Bidens pilosa</i> L. Suppress the Metastasis of Gastric Cancer Cells by Inhibiting Wnt/<i>β</i>-Catenin and Hippo/YAP Signaling Pathways

(<i>E</i>)-7-Phenyl-2-hepten-4,6-diyn-1-ol (<b>1</b>) and (<i>Z</i>)-7-Phenyl-2-hepten-4,6-diyn-1-ol (<b>2</b>) are isomeric natural polyacetylenes isolated from the Chinese medicinal plant <i>Bidens pilosa</i> L. This study first revealed...

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Bibliographic Details
Main Authors: Jing Cai, Song-Yun Shi, Fan Cheng, Min Wei, Kun Zou, Xiao-Qin Yu, Jian-Feng Chen
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Molecules
Subjects:
polyacetylene isomers
migration
invasion
Wnt/<i>β</i>-catenin
Hippo/YAP
Online Access:https://www.mdpi.com/1420-3049/28/4/1837

Internet

https://www.mdpi.com/1420-3049/28/4/1837

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